How to use: it’s a powder, sprinkles a perimeter around your bed, doorways, and anywhere else they may cross. I would also get a bedbug-proof mattress cover, encase your mattress in it and leave it closed up with some powder within for a couple of weeks at least. If you think they’re in the bed frame itself put some around the frame and anywhere they will have to travel to get to humans. Good luck.
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When you first enter your hotel room, put your luggage into the bath/shower and leave it there until you check out. If you have to move it to the shower, don’t take it out of the bathroom. Then forensically check the entire bed, mattress, behind headboards, drawers, desks.