While it’s not uncommon for these scientific journals to take a stance on policy issues, it’s absolutely remarkable for them to take an active stance against a presidential candidate, and even more so to actively endorse that candidate’s opponent. It is quite literally the first time that The Lancet, NEJM, Science, and even SciAm have ever taken an explicit stance against a candidate, or endorsed one.
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As someone that works with scientists and hopes to be one someday I can tell you that they’re notoriously anti-political, even to their detriment. They avoid even the implication of trying to support someone. These publications are fairly old and this is the first time they’ve actually endorsed anyone.