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Nurse here, I had a teenager overdose on Zoloft and start having strange seizure-like episodes. What made them particularly strange is that they all followed a predictable pattern of onset. First, he would lower the bed, next he would turn the tv volume down, and finally, he would check to see if I was nearby. There was pretty severe thrashing about without any abnormalities in breathing, heart rate, pupils and he was still able to communicate with me throughout the entire episode. Unsurprisingly, EEG also failed to show any abnormalities. The kid is lucky he didn’t give himself Serotonin Syndrome. My husband had that once (stupid ER doctor put him on Imitrex despite my husband being on Wellbutrin and Celexa) and almost didn’t make it.

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Serotonin syndrome is no joke. I’m glad he’s ok! That must have been a very frightening experience for both of you. Taking multiple different serotonin-boosting drugs is usually the main culprit for serotonin syndrome. I think this was an unfortunate case where a kid was seeking attention he may not have been getting at home. But yes, too much serotonin is definitely not a good thing. I would advise anyone taking SSRI’s to make sure their doctors are aware of all their medications before prescribing new ones and to avoid taking OTC drugs that claim antidepressant effects, like st johns wort.

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